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Evaluation of Populations and Their Health in developing countries
 

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Bandim Health Project, GAMBIA

(BANDIM DSS)

 

The Bandim DSS is located in a suburban area of the capital Bissau in Guinea-Bissau, West Africa, a former Portuguese colony, which was liberated in 1974, after a violent war. The study area comprises six suburbs of the capital and a mobile rural unit following a national cohort of women of fertile age and their children from 100 villages. The DSS has a population of more than 100 000, which is partly suburban and partly rural. After independence in 1974 an extremely high under-five mortality rate (around 500/1000 person-years observed) prompted the Ministry of Health to approach the Swedish Agency for Research Cooperation with Developing Countries to organize a study to define nutritional priorities in preventive health care. The nutrition and child-health study was initiated in 1978, and a census was carried out, with a subsequent anthropometric survey and organization of antenatal care for all women found pregnant during the census. All new pregnancies were registered, together with births, deaths, and migrations. This became the basis for the ongoing registration of the population in the Bandim suburb.

 

Objectives

  • To follow long-term consequences of various infections, health conditions and interventions.

  • To conduct research on determinants of measles mortality and evaluation of       various measles vaccination schemes.

  • To study the non-targeted immune stimulatory effects of vaccinations, vitamin A supplementation and other interventions.

  • To investigate management and health system problems in relation to disease of major impact for child mortality in low-income countries

  • To facilitate research training

 

Priority Research Areas

  • Epidemiology and control of diarrhoeal and respiratory diseases.

  • Trials of potential modifications in current health policies, including

  • BCG vaccination trials

  • Vitamin A supplementation

  • Two-dose measles vaccination trial

  • Trials to minimise the potential negative effect of DTP

  • Trial of oral polio vaccination

  • Management of childhood illnesses

  • impact of breastfeeding and weaning on morbidity and survival

  • immunological determinants of child survival

  • hospital management and mortality

  • control and treatment of malaria

  • Maternal mortality

  • Epidemiology and management of TB, HIV-2 and other retroviruses

 

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